" It ’s a very rare experience . I think we ’re cognizant of how singular this is . "

1.First,Kerry WashingtonandTony Goldwyn"never"did a chemistry read before they started filmingScandalas Olivia and Fitz.

2.Before starring as Colin and Penelope inBridgerton, Nicola Coughlan and Luke Newtondidn’t have a chemistry test, but they spent the years prior to Season 3buildingtheir friendship off-screen, so their on-screen chemistry was incredibly strong.

3.Scott Patterson and Lauren Graham didn’t have a chemistry test before they were cast as Luke and Lorelai inGilmore Girls.Theymet for the first timein a hotel in Canada, and the cast had dinner together before filming the pilot.

4.Meanwhile, Milo Ventimiglia wasofferedthe role of Jess Mariano inGilmore Girlsafter one audition and without a chemistry test alongside Alexis Bledel.

5.Due to the COVID-19 pandemic, Emma D’Arcy and Olivia Cookedidn’t doa chemistry read together before they were cast as Rhaenyra Targaryen and Alicent Hightower inHouse of the Dragon.

6.Pedro Pascal and Bella Ramsey had neverspokenbefore they were officially cast as Joel Miller and Ellie Williams inThe Last of Us. In fact, they met for the first time over Zoom during the show’s sexual harassment prevention training.

7.During the audition process for Bellamy Blake onThe 100, Bob Morley said heneverhad a chemistry read with anyone, including Eliza Taylor, who starred as Clarke Griffin. He actually booked the role within 10 days.

8.When Dan Levy was looking to cast David’s love interest forSchitt’s Creek, he hired Noah Reidwithoutdoing a chemistry test with him. The first time they read together was during the cast’s read-through for Patrick’s first episode in Season 3.

9.Quinta Brunsonactually DM’dTyler James Williams, asking him to star inAbbott Elementaryas Gregory. Tyler revealed to The Hollywood Reporter that after messaging back and forth, Quinta sent him the script, and he said yes, so there was no formal chemistry read process for the two of them.

10.Despite both of them being veteran actors, Linda Cardellini and Christina Applegate hadnever metprior toDead to Me. While they didn’t do a traditional chemistry read, they both had lunch with creator Liz Feldman prior to filming, where she really saw how great they were together.

11.Zach Braffdidn’t meetDonald Faison until the very first table read forScrubs. Despite having to play best friends J.D. and Turk, they didn’t meet during the audition process.

12.Katherine Barrell and Dom Provost-Chalkleydidn’t meetuntil Kat showed up on the set ofWynonna Earpfor the filming of the second episode when Waverly meets Nicole.

13.Freddy Carter and Amita Suman didn’t have a chemistry read before starring inShadow and Bonetogether as Kaz Brekker and Inej Ghafa. Amitatold Collider, “Freddy and I didn’t get any chemistry reads. But as soon as he walked through the door, I knew there was, at least in my eyes, the perfect Kaz.”

14.When Stefania Spampinato joinedStation 19after playing Carina DeLuca inGrey’s Anatomy, she and Danielle Savre hadnever met before, and didn’t do a chemistry read. The first time they met was during the table read for Stefania’s firstStation 19episode.

15.And finally, Emily Bett Rickards wasoriginallyonly supposed to appear in one episode ofArrowas Felicity Smoak. She didn’t have a chemistry read with Stephen Amell prior to filming, and their chemistry ultimately changed the course of the series.

More on this

Tony Goldwyn and Kerry Washington in a tense scene from Scandal

Three stills from a TV show featuring Nicola Coughlan and Luke Newton in period costumes, showcasing an intense conversation

Lauren Graham and Scott Patterson's characters share a heartfelt moment and kiss in three stills from a TV show scene

Alexis Bledel and Milo Ventimiglia in a heated conversation on the set of a TV show. Alexis wears a patterned coat, and Milo is in a denim jacket

Alicent Hightower and Rhaenyra Targaryen from House of the Dragon have a tense conversation. Alicent appears worried, and Rhaenyra looks serious

Bella Ramsey and Pedro Pascal in 'The Last of Us' sit in a post-apocalyptic setting having a serious conversation. Both wear rugged, practical outfits

Bob Morley and Eliza Taylor, characters from "The 100," in a close-up scene with intense expressions, showing concern and emotion

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Quinta Brunson and Tyler James Williams portray a couple sharing an emotional and romantic moment in several indoor scenes

Christina Applegate and Linda Cardellini in a three-panel scene from "Dead to Me," sitting and embracing while talking

Donald Faison and Zach Braff lie on the ground in casual clothes, with Zach wearing a "Hug Me!" T-shirt

Dominique Provost-Chalkley and Katherine Barrell in scenes from a TV show, with Dominique in casual wear and Katherine in a police uniform interacting with her

Amita Suman and Freddy Carter in a scene from the TV series "Shadow and Bone," wearing period costumes in a medieval-style setting

Maya Bishop and Carina DeLuca sit at a bar, talking and smiling, from the TV show "Station 19."

Stephen Amell and Emily Bett Rickards in a scene from "Arrow" as Oliver Queen and Felicity Smoak, respectively, having a heartfelt conversation over dinner

Paul Mescal and Daisy Edgar-Jones during their chemistry test for Normal People

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